NPC Biomarkers

Posted On 2023-03-13 16:02:51

The purpose of this special series on NPC biomarkers is to present an overview of conventional biomarkers used in NPC detection and monitoring, as well as include several more recent “novel” approaches for study of NPC and EBV for biomarker discovery, which are expected to identify informative biomarkers for its early detection or new biomarkers having prognostic implications. Experts in the field have been invited to provide several papers in this special series of Annals of Nasopharynx Cancer on EBV markers, as well as host biomarkers, for NPC screening, diagnosis, and prognosis and to present new avenues for NPC biomarker discovery. We expect these ongoing concerted efforts for advances in NPC diagnostics will herald in an era for improved early diagnosis and identification of targeted drugs for precision treatment of NPC.

Editorial on NPC Biomarkers
The etiology of nasopharyngeal carcinoma and challenges for its diagnosis and treatment monitoring
Maria Li Lung

EBV and NPC carcinogenesis—an alternative viewpoint
Sharon Shuxian Poh, Joseph T. S. Wee

Review Article on NPC Biomarkers
miRNA biomarkers for NPC diagnosis and prognosis
Mackenzie Fijardo, Pierre-Antoine Bissey, Kenneth W. Yip, Fei-Fei Liu

Prognostic value of Epstein-Barr virus biomarkers for nasopharyngeal carcinoma staging and post-treatment surveillance
Jacob A. Miller, Benjamin A. Pinsky, Quynh-Thu Le

Epstein-Barr virus-based nasopharyngeal carcinoma population screening
Xia Yu, Honglin Chen, Mingfang Ji

Clinical utility of circulating tumor cells for real-time serial monitoring of nasopharyngeal carcinoma patients
Josephine Mun Yee Ko

CpG methylation as epigenetic biomarkers for nasopharyngeal carcinoma diagnostics
Lili Li, Jianlian Xie, Brigette Ma, Anthony T. C. Chan, Qian Tao

Classifying the tumor microenvironment to stratify nasopharyngeal carcinoma patients
Shang-Xin Liu, Ge-Xin Zhao, Ruo-Bin Lin, Mu-Sheng Zeng, Qian Zhong

Plasma Epstein-Barr virus DNA analysis for personalised management of nasopharyngeal carcinoma—current opportunities and challenges
Wai Kei Jacky Lam, Yuk Ming Dennis Lo

Utility of Epstein-Barr virus (EBV) antibodies as screening markers for nasopharyngeal carcinoma: a narrative review
Sweta Sinha, Brittney L. Dickey, Anna E. Coghill

The series “NPC Biomarkers” was commissioned by the editorial office, Annals of Nasopharynx Cancer without any sponsorship or funding. MLL and LSY served as the unpaid Guest Editors for the series.